Substance use disorders account for 50% of annual deaths worldwide, impacting the lives and well-being of individuals and society. This on demand program is a presentation on the science of addiction focusing on the brain physiology and the circuitry. Dr. Piasecki discusses the high-jacking of the brain and illuminates the neurocircuitry disrupted in addiction, which includes circuits that mediate reward and motivation, executive control, and emotional processing. Learn about the resources on how to translate the updates into clinical practice with opioids including screening brief intervention and local resources to help our community as well as resources for coaching and consultation for providers working with patients who have opioid related problems.